THE effectiveness of meaning-based existential therapy on anxiety and serum levels of tumor necrosis factor TNFα in women with breast cancer
نویسندگان
چکیده مقاله:
Introduction: Diagnosing cancer can be a very anxious experience, and anxiety can disrupt immune system function. Tumor necrosis factor-alpha (TNFα) is an inflammatory cytokine that is associated with amplified tumor cell proliferation, higher malignancy, increased metastasis, and poor general prognosis for the patients who suffer from breast cancer. Methods: This study is a randomized clinical trial with follow-up and control group. The experimental group underwent meaning-based existential intervention. Both groups were assessed by Beck Anxiety Questionnaire and serum levels of tumor necrosis factor before, after and three months after the intervention, and data were analyzed by repeated measures analysis of variance. Results: The experimental group showed a decrease in anxiety scores and serum TNFα levels after receiving a psychotherapy program/interventions compared to the control group. The results show that the mean of TNFα was 47.10± 1.22 and the mean of anxiety was 21.75± 9.30 in the experimental group, while the mean of TNFα was 50.75± 1.71 and the mean of anxiety was 44.7± 12.27 in the control group, this reduction has also been observed in the follow-up phase (0.001≥ p). Conclusion: Based on the findings, meaning-based existential psychotherapy can reduce anxiety and serum TNFα levels by reducing patients' anxiety and helping to give meaning to life again. Accordingly, this treatment can be used along with medical treatments.
منابع مشابه
the study of aaag repeat polymorphism in promoter of errg gene and its association with the risk of breast cancer in isfahan region
چکیده: سرطان پستان دومین عامل مرگ مرتبط با سرطان در خانم ها است. از آنجا که سرطان پستان یک تومور وابسته به هورمون است، می تواند توسط وضعیت هورمون های استروئیدی شامل استروژن و پروژسترون تنظیم شود. استروژن نقش مهمی در توسعه و پیشرفت سرطان پستان ایفا می کند و تاثیر خود را روی بیان ژن های هدف از طریق گیرنده های استروژن اعمال می کند. اما گروه دیگری از گیرنده های هسته ای به نام گیرنده های مرتبط به ا...
15 صفحه اولcomparison of the effectiveness of existential – cognitive group therapy and mindfulness – based existential – cognitive on Demoralization and Experience of Pleasure in women with breast cancer
This study was conducted to compare the effectiveness of cognitive- existential and mind- based cognitive- existential therapy on the fear of cancer recurrence and its components in women with breast cancer. The method of the present study is quasi-experimental and pretest-posttest with a control group. The statistical population of this study included all women with breast cancer referred to D...
متن کامل: the effect of sericin levels (silk glue protein) on rate of in vitro maturation, fertilization and culture of sheep oocytes
هدف از آزمایش اول بررسی اثر سطوح مختلف سریسین [0 (control), 0.1, 0.5, 1.0, 2.5 %] افزوده شده به محیط , ivm بر cumulus cell expansion، بلوغ هسته و توسعه متوالی جنین، در گوسفندان نژاد سنجابی در فصل تولید مثلی می باشد. از سرگیری میوز به وسیله خارج شدن اولین پولار بادی اندازه گیری و هم چنین درصد رسیدن جنین های دو سلولی به مرحله کلیواژ و بلاستوسیت نیز به عنوان نشانه ای از میزان شایستگی توسعه اولیه ج...
Effectiveness of Cognitive-Existential Group Therapy on Life Expectancy and Anxiety of Adolescent with Cancer
Introduction: People with cancer especially adolescent, is experiencing some troubles such as anxiety, depression, and unhappiness. This study aimed to investigate the effectiveness of Cognitive-existential group therapy on life Expectancy and the anxiety of cancer diagnosed adolescent. Methods: The Research method was quasi-experimental with pretest-posttest. This study population consisted of...
متن کاملthe effect of task cognitive complexity and time limit on the performance of the learners with different proficiency levels in second language writing skill
this study investigated the effects of manipulating the cognitive complexity of tasks along +/- few elements and the time limits on l2 learners writing performance. to conduct the study, 60 iranian efl learners with two levels of proficiency, low and high intermediate, were selected and assigned to three groups based on the time devoted to task completion. the participants performed both a simp...
15 صفحه اولمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ذخیره در منابع من قبلا به منابع من ذحیره شده{@ msg_add @}
عنوان ژورنال
دوره 15 شماره 1
صفحات 87- 102
تاریخ انتشار 2022-04
با دنبال کردن یک ژورنال هنگامی که شماره جدید این ژورنال منتشر می شود به شما از طریق ایمیل اطلاع داده می شود.
کلمات کلیدی برای این مقاله ارائه نشده است
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023